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Inhibition of ferroptosis or downregulation of ACSL4 expression significantly improves clinical symptoms, reduces neuronal death, and alleviates neuroinflammation (Van San et al., 2023)

and Nascimbeni, M

Statistical Methods Change from baseline in SGRQ Total score and each component score were analyzed using analysis of covariance, with change from baseline as the response variable and with factors for treatment group, high-risk CV comorbidities (yes/no), background LABA use (yes/no), and baseline score as covariates

Similar results have been observed in animals in which the overexpression of PLIN5 in the anterior tibial muscle of male rats increased C-14-labeled palmitate ( 14 C-palmitate) oxidation in the whole muscle